FREE cancellation on most rooms!
Instant confirmation when you reserve

See how rates

  • 4.3/5 From 9,873 reviews
  • 88.1% of users recommended
St. Charles

St. Charles, MO 12 properties

Save money in St. Charles
We'll send you our best discounts
Get deals

Just Booked

    Hotels that guests love in St. Charles

    • The room was wonderful, spacious & calming. The continental breakfast, and the staff serving it, was an enjoyable way to start our day. It far exceeded what we received at other hotels. Our entire trip was much better because we stayed at Comfort Suites.

    In and Around St. Charles, Missouri

    • Cities
    • Places of Interest
    • Airports
    • Other Accommodations
    • More Hotel Themes
    • Popular Chains