FREE cancellation on most rooms!
Instant confirmation when you reserve

See how Booking.com rates

  • 4.3/5 From 9,874 reviews
  • 88% of users recommended Booking.com
Save money in St. Charles
We'll send you our best discounts
Get deals

Just Booked

    Hotels that guests love in St. Charles

    • The room was wonderful, spacious & calming. The continental breakfast, and the staff serving it, was an enjoyable way to start our day. It far exceeded what we received at other hotels. Our entire trip was much better because we stayed at Comfort Suites.

    In and Around St. Charles, Missouri

    • Cities
    • Places of Interest
    • Airports
    • Other Accommodations
    • More Hotel Themes
    • Popular Chains