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Rent the perfect Florence guesthouse at Booking.com. Find a cozy, spacious, or modern rental guesthouse in Florence Historic Center, Santa Maria Novella and Santa Croce to share with family and friends. Make yourself at home in our self catering guesthouses and plan trips to see Ponte Vecchio, Palazzo Dei Congressi and Santa Maria Novella. Booking.com has the best long stay guesthouses for rent in Florence with good availability and great rates.