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Rent the perfect Rome guesthouse at Booking.com. Find a cozy, spacious, or modern rental guesthouse in Rome City Center, Trastevere and Vatican City - Prati to share with family and friends. Make yourself at home in our self catering guesthouses and plan trips to see Roma Termini, The Colosseum and Roma Stadio Olimpico. Booking.com has the best long stay guesthouses for rent in Rome with good availability and great rates.