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Find the best rental guesthouses in Key West at Booking.com. The perfect guesthouse for rent is waiting in Duval. We have good availability and great rates so you can live like a local in a cozy guest home or a modern long stay room. Enjoy visiting Duval Street, Mallory Square and Southernmost Point from your home away from home. Booking.com has the ideal rental guesthouses or self catering accommodations for your Key West vacation.

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