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Rent the perfect Florence vacation home at Booking.com. Find cozy, spacious, or modern rental homes in Florence Historic Center, Santa Maria Novella and Santa Croce to share with family and friends. Make yourself at home in our rental apartments and plan trips to see Ponte Vecchio, Santa Maria Novella and Palazzo Dei Congressi . Booking.com has the best cottages and guest rooms for rent in Florence with good availability and great rates.