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Find the best rental vacation home in San Diego at Booking.com. The perfect guesthouse for rent is waiting in Gaslamp Quarter, Pacific Beach and Mission Valley. We have good availability and great rates so you can live like a local in a modern chalet or a cozy cottage. Enjoy visiting SeaWorld San Diego, San Diego Convention Center and Downtown San Diego from your home away from home. Booking.com has the ideal rental house or vacation home for your San Diego trip.

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