My wife and I are from San Francisco, and I did a ton of research on hotels and honeymoon destinations all over the world before settling on the Greek Islands. We traveled from SF to spend a night in London, then direct from Heathrow to Thira (Santorini's other name) for the next three nights of our amazing honeymoon (we're in Mykonos now).
The reception had emailed me a couple weeks before to ask if we wanted a driver to pick us up at the airport (a "transfer") and we took them up on it to make the trip as easy as possible because I had read that it was difficult to "find" hotels in Santorini since they're all bunched up together. A guy was waiting with a sign for us once we landed (who doesn't like feeling like a star when leaving an airport???), and drove us to the reception area in Imergovigli. A hotel staff member was there waiting for us, and carried two of our super heavy, huge suitcases down a long flight of stairs to our room while he pointed us to a secondary reception very close to our soon-to-be-palace. To my point that the hotels are clustered so tightly together, some poor guy on holiday was lugging around three bags looking lost that we came across on the walk down the stairs asking us if we knew of some place that I don't think was anywhere near by.
If you've never been to Santorini, you're blown away at the breathtaking views and phenomenal beauty of the whole place--blue skies, sea, cliffs, white houses--wow. Check in was painless and we were given a list of restaurants to check out and we went to two while there (1800 was great).
The honeymoon suite was amazing with the hot tub on the deck overlooking the Caldera. Breakfast was delicious and had us getting up early to make sure we got to eat it on our private balcony.
The staff was very helpful, but unobtrusive. We rented an ATV and used that to get around the island. I'd recommend that for you as well.
It's expensive. My justification of spending the big bucks was that I'll never look back and regret spending money on an amazing experience, but I definitely would regret having a sub-par experience on my honeymoon!
All of the hotels on the Caldera are expensive as there is a limited number of rooms and an increasing number of visitors every year. It's all about location, location, location, and you want to be staying in Imergovigli -- between Oia and Fira. You want a room with a hot tub on the deck. You want breakfast delivered to your room. So you pay! ;)
Other than that, I didn't like having to leave!