Choose your preferred language. We speak English and 41 other languages.
Most often used by people in the United States
Via Cicerone 39, Vatican City - Prati, 00193 Rome – Show map
Get instant confirmation with FREE cancellation on most rooms!
The most recent booking for this hotel was made on Aug 21 at 1:48 PM from Italy.
6 Reasons to Choose Hotel Isa
No booking fees • Save money! Best price guarantee — enter dates to see these prices!
4144 properties in Rome
Including hotels, apartments, villas and more.
We speak your language
Hotel Isa's staff speak: Italian, English, German
Booking is safe
When you book with us your details are protected by a secure connection.
Food & Drink
Bar, Breakfast in the Room, Snack Bar
Free! WiFi is available in the hotel rooms and is free of charge.
Private parking is available at a location nearby (reservation is not possible) and charges apply.
Airport Shuttle, Car Rental, Shuttle Service (surcharge), Airport Shuttle (surcharge), 24-Hour Front Desk, Express Check-in/Check-out, Baggage Storage, Concierge Service, Laundry, Dry Cleaning, Ironing Service, Shoeshine, Meeting/Banquet Facilities, Fax/Photocopying, VIP Room Facilities, Honeymoon Suite
Newspapers, Safe, Non-smoking Rooms, Family Rooms, Elevator, Soundproof Rooms, Heating, Hypoallergenic room available, All Spaces Non-Smoking (public and private), Air Conditioning, Designated Smoking Area
Italian, English, German
From 3:00 PM
Until 11:00 AM
My viewed hotels
Right next to the Vatican City and a 10-minute walk from Saint Peter's Square, Starhotels Michelangelo Rome has rooms with classic decoration and air conditioning.
Score from 1545 reviews Excellent - 8.7/10
The Twentyone is a modern boutique hotel on Via Cola di Rienzo, one of Rome's best shopping streets. Castel Sant'Angelo and the historic center are just a pleasant 10-minute walk away.
Score from 1341 reviews Very good - 8.4/10
The 4-star Hotel Giulio Cesare is in an elegant 19th-century building in the prestigious Prati area of central Rome, 320 yards from Lepanto Metro Station.
Score from 416 reviews Very good - 8.3/10
In a 19th-century building, the Quirinale is a 10-minute walk from the Colosseum. This historic hotel is connected to Rome Opera House through a passageway in its leafy courtyard.
Score from 3305 reviews Very good - 8.1/10
We've negotiated with thousands of hotels to get the very best deals. We call them Secret Deals and they only last for a limited time.
You can get these deals for free by subscribing to our newsletters. You can even choose your favorite destinations to receive personalized deals.
Get started now by entering your email address. We'll instantly send you a link to our Deal Finder!
Don't worry – your email address is safe with us. We'll never share your private information and you can unsubscribe at any time.