I can't think of a single downfall - staying here is definitely the way to go!
This is my second time staying at Locanda Carmel, the first was in 2008 with my brother and 93yr old grandfather. This 2014 trip was for my honeymoon, and although Rome offers many hotel options, I insisted we stay at "the Locanda". Since 2008 they now offer a continental breakfast at the hotel. You are centrally located in Rome; easily in walking distance to The Colosseum, Piazza Navona, Piazza Venecia, the Roman Forum, Fountain Di Trevi and the Pantheon, just to name a few. If you're not too keen on walking, the Tram (which leads to the city center) is literally a block away, and there is a bus that goes to the Vatican up the street. Some of the best food we ate was right next door. Staying at Locanda makes your trip so much more authentic; you are not surrounded by tourists, rather locals who love to engage in conversation and help in any way. Claudia at reception was absolutely fantastic and helped my husband and I with all of our needs, in and out of the hotel. Not to mention the gorgeous garden terrace! One thing is for sure, when I do return to Rome, I will stay here for a 3rd time, I wouldn't ever consider another place!