Search business hotels in South Carolina

More than 1 million people last month said they'd recommend Booking.com to their family and friends.

FREE cancellation on most rooms! Instant confirmation when you reserve

  • 5,315 properties in South Carolina
    Show map Map
  • North Charleston, United States of America
    8.9

    Excellent

    555 reviews

    This Charleston, South Carolina hotel is on the campus of Charleston Southern University. A hot breakfast buffet, outdoor pool, and hot tub are provided. The Naval Weapons Station is 8.5 miles away.

  • Columbia, United States of America
    8.7

    Excellent

    251 reviews

    The Best Western Plus Columbia North East provides a daily hot breakfast for guests and free Wi-Fi in the rooms. This hotel is a 15-minute drive from the center of the city of Columbia.

  • Greenville, United States of America
    8.0

    Very Good

    600 reviews

    Enjoy convenient amenities at this hotel. Located minutes from downtown's restaurants and shopping, a free airport shuttle service is available from Greenville-Spartanburg Airport.

  • North Charleston, United States of America
    8.9

    Excellent

    256 reviews

    This downtown Charleston hotel provides a free shuttle to Charleston International Airport, 1 mile away.

  • Charleston, United States of America
    8.7

    Excellent

    142 reviews

    This hotel in Charleston is 12 miles from Charleston Airport. It has a rooftop lounge with views of the Ashley River, an outdoor pool and a gym.

  • North Charleston, United States of America
    7.8

    Good

    105 reviews

    This hotel is 10 miles from historic downtown Charleston and 3 miles from the Charleston AFB/ International Airport. The hotel provides a free airport shuttle and rooms with a flat-screen TV.

  • Greenville, United States of America
    6.7

    Review score

    192 reviews

    Just off Interstate 385, this hotel is within a 10-minute drive of downtown Greenville. The hotel offers an outdoor swimming pool, free Wi-Fi and a daily continental breakfast.

  • Greenville, United States of America
    8.9

    Excellent

    69 reviews

    The Greenville Crowne Plaza Hotel is a 10 minute drive from the Greenville Zoo. Guests of this hotel will enjoy 2 restaurants and an indoor pool on site along with a flat-screen TV in each room.

  • Myrtle Beach, United States of America
    8.3

    Very Good

    329 reviews

    Connected to Myrtle Beach Convention Center in the city's business district, this South Carolina hotel offers in-room massages, on-site dining and an indoor heated pool with a deck.

  • Columbia, United States of America
    8.2

    Very Good

    107 reviews

    Located off Interstate-20, this hotel is 6.5 miles from downtown Columbia and the University of South Carolina. It features an Italian restaurant and spacious rooms with a 32-inch flat-screen TV.

You might also like these property types: