Hotels in Santo Spirito, Florence
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Featured Hotels in Santo Spirito
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Palazzo Martellini Residenza d'epoca
Palazzo Martellini Residenza d'epoca features accommodations in the center of Florence, a 3-minute walk from Pitti Palace and 600 yards from Strozzi Palace.

SPIRIT OF FLORENCE Boutique Rooms
SPIRIT OF FLORENCE Boutique Rooms features free Wifi and rooms with air conditioning in Florence.

Palazzo Ridolfi - Residenza d'Epoca
Located in Florence and with Pitti Palace reachable within a 3-minute walk, Palazzo Ridolfi - Residenza d'Epoca has express check-in and check-out, allergy-free rooms, a shared lounge, free WiFi...

Althea Rooms
Located on the less touristy side of the Arno River, a 3-minute walk from Piazza di Santo Spirito, Althea Rooms offers free WiFi, and the owners will amaze you with their excellent customer service...

San Pier Novello in Oltrarno
Offering air-conditioned rooms in the Santo Spirito district of Florence, San Pier Novello in Oltrarno is a 12-minute walk from Strozzi Palace.

Piazza Pitti Palace - Residenza d'Epoca
Set in a historic building and featuring free WiFi throughout, Piazza Pitti Palace offers accommodations in Florence, 328 feet from Pitti Palace.

Palazzo Bianca Cappello Residenza d'Epoca
In a prime location in the center of Florence, Palazzo Bianca Cappello Residenza d'Epoca is within a 3-minute walk of Pitti Palace and 700 yards of Strozzi Palace.

Toscanelli Residenza d'Epoca
Right in the heart of Florence, Toscanelli Residenza d'Epoca features rooms with free Wifi. There's a private entrance at the guest house for the convenience of those who stay.

Hotel Palazzo Guadagni
Palazzo Guadagni Hotel is set in a 16th-century building in a quiet square a 5 minute walk from the Ponte Vecchio. It has a roof garden with lovely views.

Soprarno Suites
Centrally located in Florence, Soprarno Suites is a 5-minute walk from the Ponte Vecchio bridge. It offers free Wi-Fi and elegant spacious rooms.

Most booked hotels in Santo Spirito in the past month
Popular with guests booking hotels in Florence
Scored out of 10, guest rating 8.5Very Good - What previous guests thought, 1,545 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.4Wonderful - What previous guests thought, 1,199 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 8.6Excellent - What previous guests thought, 1,913 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.2Wonderful - What previous guests thought, 387 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 8.8Excellent - What previous guests thought, 800 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.4Wonderful - What previous guests thought, 877 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 8.2Very Good - What previous guests thought, 783 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.2Wonderful - What previous guests thought, 324 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.2Wonderful - What previous guests thought, 439 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.3Wonderful - What previous guests thought, 210 reviews
The best hotels with breakfast in Santo Spirito
Palazzo Ridolfi - Residenza d'Epoca
Hotel in Santo Spirito, FlorenceBreakfast optionsScored out of 10, guest rating 9.4Wonderful - What previous guests thought, 1,199 reviewsLocated in Florence and with Pitti Palace reachable within a 3-minute walk, Palazzo Ridolfi - Residenza d'Epoca has express check-in and check-out, allergy-free rooms, a shared lounge, free WiFi...
From $530.23 per night- Scored out of 10, guest rating 9.3Wonderful - What previous guests thought, 210 reviews
In a prime location in the center of Florence, Palazzo Bianca Cappello Residenza d'Epoca is within a 3-minute walk of Pitti Palace and 700 yards of Strozzi Palace.
From $574.50 per night Ponte Vecchio Suites & Spa
Hotel in Santo Spirito, FlorenceBreakfast optionsScored out of 10, guest rating 9.2Wonderful - What previous guests thought, 439 reviewsLocated 2 minutes’ walk from Florence's most famous bridge Ponte Vecchio, Ponte Vecchio Suites & Spa is set in the heart of the historic center.
From $608.56 per nightHotel Palazzo Guadagni
Hotel in Santo Spirito, FlorenceBreakfast optionsScored out of 10, guest rating 9.2Wonderful - What previous guests thought, 387 reviewsPalazzo Guadagni Hotel is set in a 16th-century building in a quiet square a 5 minute walk from the Ponte Vecchio. It has a roof garden with lovely views.
Check out other unique places to stay in Santo Spirito
Family Hotels
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95 pet-friendly hotels in Santo SpiritoBoutique Hotels
6 boutique hotels in Santo SpiritoGuest Houses
10 guest houses in Santo SpiritoAccessible Hotels
5 accessible hotels in Santo SpiritoApartments
126 apartments in Santo SpiritoB&Bs
13 B&Bs in Santo SpiritoServiced apartments
5 serviced apartments in Santo Spirito
Places of interest in and around Santo Spirito
Find hotels near attractions, museums, and other landmarks
Porta Romana, Florence, Florence
LandmarksVia Maggio, Florence
Popular AreasPitti Palace, Florence
MuseumsCappella Brancacci, Florence
LandmarksConsulate General of Brazil – Florence, Florence
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