Search flights from Houston (HOU) to Santiago (SCL)

Book your plane tickets from Houston to Santiago with ease

Cheapest flights to Santiago

The cheapest flights available in the next 60 days – prices are updated regularly

Flying from Houston to Santiago: things to know

The most popular route is from George Bush Intercontinental Airport in Houston to Santiago International Airport in Santiago. On average this flight takes 18 hours 16 minutes one-way and costs $1,007 round-trip.

Most popular route
George Bush Intercontinental Airport (IAH) to Santiago International Airport (SCL)
Average flight time
18 hours 16 minutes
Average round-trip price
$1,007
Fly from Houston to Santiago
7 airlines

Reasons to book flights with Booking.com

  • Great selection

    Easily compare flights, airlines, and prices – all in one place

  • No hidden fees

    Always know exactly what you’re paying for

  • Flexibility

    Use our flexible plane ticket option to change your dates if needed

Flexible plane ticket options are available for an additional cost on select airfares

Airlines that fly from Houston to Santiago

Airline options may vary according to recently booked flights and your search terms

  • Avianca
  • United Airlines
  • Copa Airlines
  • Spirit Airlines
  • American Airlines
  • Aeromexico
  • Air Canada

Frequently asked questions

Fly to more destinations from Houston

gogless