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Wanna go somewhere wonderful? Reviewers loved San Diego!

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A house makes a home. Explore the very best vacation homes we have to offer.

More than 1 million people last month said they'd recommend Booking.com to their family and friends.

  • The 10 Best Vacation Homes in San Diego, USA

    Check out our selection of great vacation houses in San Diego

Looking for a holiday house?

Great for families or large parties, vacation homes are privately owned accommodations, available for long or short-term rental. These homes are furnished and equipped with kitchen facilities, though breakfast might be offered as an add-on. These properties have their own independent front door, which makes them different than apartments.

Most Booked Vacation Homes in San Diego This Month

Beautiful Downtown San Diego Suites by Sonder

Downtown San Diego, San Diego, CA 92101, United States of America

8.4 Very Good 12 vacation home reviews

This vacation home in San Diego has been booked 55 times.

Charming Little Italy Suites by Sonder

Downtown San Diego, San Diego, CA 92101, United States of America

8.3 Very Good 10 vacation home reviews

This vacation home in San Diego has been booked 23 times.

Redwood Hollow Cottages

La Jolla, San Diego, 92037, United States of America

8.9 Excellent 117 vacation home reviews

This vacation home in San Diego has been booked 17 times.

Airy North Park Suites by Sonder

San Diego, CA 92104, United States of America

9.1 Awesome 17 vacation home reviews

This vacation home in San Diego has been booked 17 times.

OB Cottage Near Beach!!!

Ocean Beach, San Diego, CA 92107, United States of America

6.6 Review score 12 vacation home reviews

This vacation home in San Diego has been booked 12 times.

Lofty Pursuits

Downtown San Diego, San Diego, 92101, United States of America

This vacation home in San Diego has been booked 9 times.

Vacation Homes That Guests Love in San Diego

Rodeway Inn San Diego Near Qualcomm Stadium

“The beds and pillows are great. Also the room was very clean. The hotel is located near an innerstate but with the windows closed you couldn't hear a thing. ”

Aug 28, 2018

Amazing Triplex in Downtown San Diego #1

“The apartment is extremely nice and in a very convenient location, 10 mins walking from the Gaslamp bar street. The 2 bedrooms with attached bathrooms are perfect for 2 couples or friends travelling together. The kitchen is very clean and equipped. Underground parking available (essential if travelling by car).”

Aug 27, 2018

Horton Grand Hotel

“Excellent value for money - really comfy room with nice period decor but modern facilities. In the centre of the gaslamp quarter but not too noisy. Very clean, and nice having a balcony to sit on and watch the sun set. Great stay.”

Aug 25, 2018

Urban Boutique Hotel

“The location is great, you can find the best restaurants vary close. the staff (all of them) are amazing and very helpful. The bathroom and the room were very clean.”

Aug 25, 2018

La Quinta Inn & Suites San Diego Mission Bay

“Breakfast was excellent, the rooms are nice, very good value for money. Rooms were very clean. I can reccomend for everybody”

Aug 23, 2018

Comfort Inn Gaslamp Convention Center

“Good location, very clean, small but comfortable room, good breakfast.”

Aug 22, 2018

ITH Adventure Hostel San Diego

“The excellent staff and hostess. The bathroom is very clean. And the environment is quiet for sleep.”

Aug 22, 2018

HI San Diego Point Loma Hostel

“Nice staff, very clean, good breakfast, free surfboards and coffee. Has everything you need!!! Great hostel!”

Aug 22, 2018

Sheraton San Diego Hotel & Marina

“Food was great, view was amazing, staff was slightly confused about things. I got wrong information on payment twice. They were very helpful no doubt, but gave me wrong info concerning my payment methods. Anyway, overall I had a good time, so I overlooked that. Also, the gym was medium sized, but nice and well equipped. The room was very clean, with a soothing view and balcony.”

Aug 21, 2018

Days Inn by Wyndham San Diego Hotel Circle Near SeaWorld

“Very Clean, comfy beds, big room. You can park a car just near your door. Good location to many places in SD, only better will be La Jolla or pb near the ocean ;) pool was intimate, hidden in trees — all the time i was alone there, like a private pool ! And great price! Little Restaurant bunz ar the hotel if you want to eat hot breakfast :) ”

Apr 28, 2018

Not just holiday houses – we have these places to stay too!