Via Cola Di Rienzo 23, Vatican City - Prati, 00195 Rome, Italy – Excellent location – show map
Excellent location – rated 9.1/10! (score from 2875 reviews)
Rated by guests after their stay at Twentyone Hotel.
An unforgettable experience in the heart of Rome
Twentyone Hotel takes special requests – add in the next step!
Area Info – Great location - show map
- Piazza Cavour 0.2 miles
- Lepanto Metro Station 0.2 miles
- Piazza del Popolo 0.4 miles
- Ara Pacis 0.4 miles
- Piazzale Flaminio 0.4 miles
- Castel Sant'Angelo 0.4 miles
- Flaminio Metro Station 0.5 miles
- Castel Sant'Angelo Museum 0.5 miles
- St. Angelo Bridge 0.5 miles
- Via Margutta 0.5 miles
Most Popular Landmarks
- Piazza di Spagna 0.7 miles
- Piazza Navona 0.7 miles
- Vatican Museums 0.8 miles
- St. Peter's Basilica 0.9 miles
- Trevi Fountain 0.9 miles
- Campo de' Fiori 0.9 miles
- Roman Forum 1.4 miles
- Roma Termini 1.7 miles
- Trastevere 1.7 miles
- The Colosseum 1.8 miles
Restaurants & Markets
- sma Supermarket 0.1 miles
- Ciampino Airport 9.8 miles
- Fiumicino Airport 13.7 miles
Food Areas Nearby
- Piazza di Spagna Restaurant Nightlife area with bars Wine bar Food in this area includes: Bar snacks, Gourmet, Italian, Traditional, Sandwiches, Seafood
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6 Reasons to Choose Twentyone Hotel
Prices you can't beat!
Manage your bookings online
The staff speaks English
Booking is safe
One of our top picks in Rome
Pets are not allowed.
Food & Drink
- Kids' Meals (additional charge)
- Snack Bar
- Breakfast in the Room
- Restaurant (à la carte & buffet)
Free! WiFi is available in all areas and is free of charge.
Private parking is available on site (reservation is needed) and costs EUR 20 per day.
Front Desk Services
- Concierge Service
- Baggage Storage
- Tour Desk
- Express Check-in/Check-out
- 24-Hour Front Desk
Entertainment & Family Services
- Kids' TV Networks
- Laundry (additional charge)
- Shared Lounge/TV Area
- Airport Shuttle (additional charge)
- Shuttle Service (additional charge)
- Designated Smoking Area
- Air Conditioning
- Soundproof Rooms
- Family Rooms
- Facilities for Disabled Guests
- Non-Smoking Rooms
- Room Service
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2:00 PM - 12:00 AM
7:00 AM - 11:00 AM
Cancellation and prepayment policies vary according to room type. Please enter the dates of your stay and check what conditions apply to your preferred room.
Children and Extra Beds
All children are welcome.
There is no capacity for extra beds in the room.
Pets are not allowed.
Cards accepted at this property
Hover over the cards for more info.