Stay in the heart of Louisville Excellent location – show map

The Louisville 21c Museum Hotel is located downtown, within walking distance of the Louisville Slugger Museum, and features an art museum, restaurant and spa. Rooms have 42-inch flat-screen cable TVs.

The luxurious guest rooms provide minibars. They have free Wi-Fi and iPod docking stations and also include desks and laptop safes. The bathrooms provide bathrobes and hairdryers.

A sauna, gym, and bike rentals are available at 21c Museum Hotel. The hotel has a business center and banquet facilities.

The centrally located 21c Museum Hotel is within a half mile of the Kentucky Museum of Art & Craft, the Frazier International History Museum and the Muhammad Ali Center. It is one mile from Louisville Slugger Field and University of Louisville and 6 miles from Louisville International Airport.

Couples in particular like the location – they rated it 9.1 for a two-person trip.

21c Museum Hotel Louisville has been welcoming guests since Jun 23, 2011
Hotel chain/brand: 21c Museum Hotels

ATM: Need cash? This property has an ATM on site.

Property Highlights

Top Location: Highly rated by recent guests (9.3)

Great Food: Meals here are highly recommended!

Breakfast Info



Select dates to see this property's availability and prices

Room Type
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4 reasons to choose 21c Museum Hotel Louisville

  • Prices you can't beat!
  • Booking is safe
  • Manage your bookings online
  • The staff speaks English
Property questions and answers
Browse questions from guests for anything extra you want to know about the property
The property usually replies within a few days
  • Is there a balcony
    Hello- Our Luxury Kings rooms do not have a balcony. We do have 2 balcony suites and 1 penthouse that has a 2000 sq. ft. terrace. Please let me know i...
    Answered on July 25, 2019
  • Dear Sir/Madame, Could you please tell us the cost for 2 small dogs under 20 lbs? Thankyou,
    Hello- we have a $75 pet fee per room. Please let me know if you need any additional info. Best,
    Answered on December 30, 2019
  • I need a room with a tub
    Hi Traveler, All of our Deluxe Double Room's come with tubs. We look forward to your upcoming stay. Best,
    Answered on August 13, 2019
  • Hi, do you have rooms with soaking tubs?
    Hello, We do not have soaking tubs in our guest rooms. We do have some rooms with standard size bathtubs. Best, Sean Ridgeway | Front Office Su...
    Answered on November 3, 2021
  • Do you have a honeymoon suite and honeymoon packages ?
    We can turn any of our suites into a honeymoon suite with the inclusion of our Love Birds Package! It will include; $100 dinner credit at Proof on Ma...
    Answered on August 13, 2022
  • Still looking?
Hotel area info *
Guests loved walking around the neighborhood!
Excellent location – show map
1 Restaurant On Site

    Proof on Main

    Food: American

Travel Proud

Travel Proud

This is a Proud Certified property where you can be extra sure of a welcoming stay.

Amenities of 21c Museum Hotel Louisville
  • Temporary art galleries
Food & Drink
  • Fruit Additional charge
  • Wine/Champagne Additional charge
  • Bar
  • Restaurant
No internet access available.
Parking options available
  • Electric vehicle charging station
  • Parking garage
  • Secure parking
Front Desk Services
  • Concierge
  • ATM on site
  • Baggage storage
  • 24-hour front desk
Cleaning Services
  • Daily housekeeping
  • Suit press Additional charge
  • Ironing service Additional charge
  • Dry cleaning Additional charge
  • Laundry Additional charge
Business Facilities
  • Fax/Photocopying
  • Business center
  • Meeting/Banquet facilities Additional charge
Safety & security
  • Fire extinguishers
  • Smoke alarms
  • Security alarm
  • Safe
  • Pet bowls
  • Air conditioning
  • Smoke-free property
  • Hypoallergenic room available
  • Heating
  • Soundproof rooms
  • Elevator
  • Facilities for disabled guests
  • Non-smoking rooms
  • Room service
  • Wheelchair accessible
Health & Wellness Facilities
  • Locker rooms
  • Yoga classes
  • Fitness
  • Full-body massage Additional charge
  • Steam room
  • Spa facilities
  • Turkish/Steam Bath
  • Massage Additional charge
  • Spa Additional charge
  • Fitness center
  • Sauna
Languages Spoken
  • English
Sustainability initiatives
This property has taken steps to provide more sustainable and eco-friendly travel

House rules 21c Museum Hotel Louisville takes special requests – add in the next step!


From 4:00 PM

Guests are required to show a photo ID and credit card at check-in


Until 11:00 AM


Cancellation and prepayment policies vary according to accommodations type. Please enter the dates of your stay and check what conditions apply to your preferred room.

Children & Beds

Child policies

Children of all ages are welcome.

Children 18 and above are considered adults at this property.

To see correct prices and occupancy info, add the number and ages of children in your group to your search.

Crib and extra bed policies

0+ years
Extra bed by request
$0 per person, per night

Additional fees are not calculated automatically in the total cost and will have to be paid for separately during your stay.

There's no capacity for cribs at this property.

The maximum number of extra beds allowed depends on the room you choose. Double-check the maximum capacity for the room you selected.

All cribs and extra beds are subject to availability.

No age restriction

There's no age requirement for check-in


Pets are not allowed.


When booking more than 7 rooms, different policies and additional supplements may apply.

Mastercard Visa American Express 21c Museum Hotel Louisville accepts these cards and reserves the right to temporarily hold an amount prior to arrival.

The fine print

Upon check-in photo identification and credit card is required. All special requests are subject to availability upon check-in. Special requests cannot be guaranteed and may incur additional charges.

Guests under the age of 21 can only check in with a parent or official guardian.

The property offers valet parking for USD 32 per night, per car, with unlimited in/out privileges.

Food and beverage services at this property may be limited or unavailable due to the coronavirus (COVID-19).

Due to the coronavirus (COVID-19), this property is taking steps to protect the safety of guests and staff. Certain services and amenities may be reduced or unavailable as a result.

Due to coronavirus (COVID-19), this property adheres to strict physical distancing measures.

Due to the coronavirus (COVID-19), wearing a face mask is mandatory in all indoor common areas.

Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply.

FAQs about 21c Museum Hotel Louisville

  • The prices at 21c Museum Hotel Louisville may vary depending on your stay (e.g. dates, hotel's policy etc.). To see prices, enter your dates.

  • 21c Museum Hotel Louisville offers the following activities/services (charges may apply):

    • Spa
    • Fitness center
    • Sauna
    • Massage
    • Turkish/Steam Bath
    • Fitness
    • Spa facilities
    • Steam room
    • Locker rooms
    • Yoga classes
    • Temporary art galleries
    • Full-body massage

  • Room options at 21c Museum Hotel Louisville include:

    • Double
    • Suite

  • Check-in at 21c Museum Hotel Louisville is from 4:00 PM, and check-out is until 11:00 AM.

  • From the nearest airport, you can get to 21c Museum Hotel Louisville by:

    • Car 14min

  • 21c Museum Hotel Louisville has 1 restaurant:

    • Proof on Main

  • 21c Museum Hotel Louisville is 1,300 feet from the center of Louisville.

  • Guests staying at 21c Museum Hotel Louisville can enjoy a highly-rated breakfast during their stay (guest review score: 7.5).

    Breakfast option(s) include:

    • American
    • À la carte