Search hotels in Santa Cruz Region, Bolivia
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Check out these popular cities in Santa Cruz Region
Santa Cruz de la Sierra
1019 hotelsSamaipata
65 hotelsIsla del Mono
3 hotelsEl Pari
40 hotelsLa Playa Bejarano
41 hotelsHamacas
9 hotelsCamiri
2 hotelsBuena Vista
12 hotelsVila El Carmen
5 hotelsVallegrande
5 hotels
Stay in Santa Cruz Region's best hotels!
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Cosmopolitano Hotel Boutique
Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical center of Santa Cruz de la Sierra. Guests can enjoy the on-site bar.

TRYP by Wyndham Santa Cruz
Located in Santa Cruz de la Sierra, a 19-minute walk from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz has accommodations with an outdoor swimming pool, free private parking,...

YVY CASA HOTEL
Located in Samaipata, 6.1 miles from Samaipata Fort, YVY CASA HOTEL provides accommodations with a garden, free private parking and a terrace.

Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness center, a shared lounge and terrace in Santa Cruz de la Sierra.

El Pueblito Hotel Boutique
Located in Samaipata, 7 miles from Samaipata Fort, El Pueblito Hotel Boutique has accommodations with an outdoor swimming pool, free private parking, a garden and a shared lounge.

Hotel Cortez
Boasting an outdoor swimming pool, gym and spa facilities, Hotel Cortez has chic and spacious rooms in Santa Cruz de la Sierra. Free WiFi access is available.

Hotel By Armonía Santa Cruz
Located in Santa Cruz de la Sierra, a 19-minute walk from Güembé Biocentre and Guazú Ivaga Park, Hotel By Armonía Santa Cruz has accommodations with an outdoor swimming pool, free private parking, a...

La Vida es Bella
Located in Samaipata, 5.6 miles from Samaipata Fort, La Vida es Bella provides accommodations with a garden, free private parking, a shared lounge and a terrace.

Chairu Eco Hotel
Chairu Eco Hotel features an outdoor swimming pool, shared lounge, a terrace and restaurant in Santa Cruz de la Sierra.

Swissotel Santa Cruz de La Sierra
Located in Santa Cruz de la Sierra, 2.8 miles from Gabriel Rene Moreno Autonomous University, Swissotel Santa Cruz de La Sierra has accommodations with an outdoor swimming pool, free private parking,...

Most-booked hotels in Santa Cruz Region in the past month
Popular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.9Excellent - What previous guests thought, 244 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 9.1Wonderful - What previous guests thought, 1,112 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.9Excellent - What previous guests thought, 798 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.7Excellent - What previous guests thought, 368 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.8Good - What previous guests thought, 1,144 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 9.0Wonderful - What previous guests thought, 595 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.7Good - What previous guests thought, 211 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.5Good - What previous guests thought, 556 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.8Excellent - What previous guests thought, 487 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 6.3Pleasant - What previous guests thought, 271 reviews
Santa Cruz Region's best hotels with breakfast
Novotel Santa Cruz De La Sierra
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.7Excellent - What previous guests thought, 181 reviewsLocated in Santa Cruz de la Sierra, 2.2 miles from Gabriel Rene Moreno Autonomous University, Novotel Santa Cruz De La Sierra has accommodations with an outdoor swimming pool, free private parking, a...
From $105 per nightChairu Eco Hotel
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.9Excellent - What previous guests thought, 798 reviewsChairu Eco Hotel features an outdoor swimming pool, shared lounge, a terrace and restaurant in Santa Cruz de la Sierra.
From $80 per nightSwissotel Santa Cruz de La Sierra
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.9Excellent - What previous guests thought, 291 reviewsLocated in Santa Cruz de la Sierra, 2.8 miles from Gabriel Rene Moreno Autonomous University, Swissotel Santa Cruz de La Sierra has accommodations with an outdoor swimming pool, free private parking,...
From $148 per nightDelfines Collection Hotel by Mercure
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.0Very Good - What previous guests thought, 303 reviewsLocated in Santa Cruz de la Sierra, 1.4 miles from Gabriel Rene Moreno Autonomous University, Delfines Collection Hotel by Mercure provides accommodations with an outdoor swimming pool, free private...
From $62.57 per nightHampton by Hilton Santa Cruz
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.7Excellent - What previous guests thought, 368 reviewsLocated in Santa Cruz de la Sierra, 1.3 miles from Gabriel Rene Moreno Autonomous University, Hampton by Hilton Santa Cruz provides accommodations with a fitness center, free private parking, a garden...
From $121.26 per nightMai Suites Apart Hotel
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.7Excellent - What previous guests thought, 163 reviewsFeaturing 5-star accommodations, Mai Suites Apart Hotel is located in Santa Cruz de la Sierra, 1.2 miles from Gabriel Rene Moreno Autonomous University and 2.6 miles from Arenal Park.
From $85 per nightLP Equipetrol
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.0Very Good - What previous guests thought, 388 reviewsLocated in the commercial district of Equipetrol, this property offers accommodations with free WiFi access in Santa Cruz de la Sierra.
From $66.89 per nightHotel Sirari By Regina
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.5Very Good - What previous guests thought, 252 reviewsLocated in Santa Cruz de la Sierra, 1.2 miles from Gabriel Rene Moreno Autonomous University, Hotel Sirari By Regina has accommodations with an outdoor swimming pool, free private parking, a fitness...
From $95 per night
Budget hotels in Santa Cruz Region
- Scored out of 10, guest rating 8.3Very Good - What previous guests thought, 318 reviews
The LP Santa Cruz Hotel is a 3-star hotel located few yards from Blacutt Square in central Santa Cruz. It offers rooms with cable TV, a mini-bar and free Wi-Fi.
From $61.83 per night - Scored out of 10, guest rating 8.0Very Good - What previous guests thought, 43 reviews
Located in Santa Cruz de la Sierra, a few steps from Sacred Art Museum, Pascana Hotel provides accommodations with an outdoor swimming pool, free private parking, a terrace and a restaurant.
From $74.80 per night Hotel Maywa
Hotel in Santa Cruz de la SierraCheap hotelScored out of 10, guest rating 8.8Excellent - What previous guests thought, 80 reviewsLocated in Santa Cruz de la Sierra, 1.9 miles from Güembé Biocentre and Guazú Ivaga Park, Hotel Maywa has accommodations with a fitness center, free private parking, a shared lounge and a terrace.
From $48.45 per night- Scored out of 10, guest rating 7.8Good - What previous guests thought, 1,144 reviews
Featuring an outdoor pool, La Siesta Hotel offers accommodations in Santa Cruz de la Sierra. Free WiFi access is available.
From $63.28 per night - Scored out of 10, guest rating 6.3Pleasant - What previous guests thought, 271 reviews
Located in Santa Cruz de la Sierra, within 8.9 miles of Arenal Park and 9.1 miles of 24th of September Metropolitan Plaza, Hotel Viru Viru II provides accommodations with a fitness center and free...
From $42.50 per night Hotel Arenal
Hotel in Santa Cruz de la SierraCheap hotelScored out of 10, guest rating 7.5Good - What previous guests thought, 188 reviewsFeaturing a swimming pool, a fitness center and a restaurant, Hotel Arenal offers rooms with free Wi-Fi and flat-screen TVs in Santa Cruz de la Sierra. Free parking is provided.
From $69.90 per night- Scored out of 10, guest rating 4.8Disappointing - What previous guests thought, 4 reviews
Mansión By Hotel Casablanca is a 2-star property located in Samaipata. Samaipata Fort is 5.7 miles from the hotel.
From $42.90 per night - Scored out of 10, guest rating 7.8Good - What previous guests thought, 9 reviews
Hotel Boutique Plaza24 has a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a shared kitchen and room service.
From $60 per night
Hotels in Santa Cruz Region you can book without a credit card
LA CASONA Hotel Boutique
Hotel in CamiriNo credit card neededScored out of 10, guest rating 8.4Very Good - What previous guests thought, 17 reviewsFeaturing a terrace and barbecue facilities, LA CASONA Hotel Boutique is located in Camiri.
From $40 per nightEx Hotel Asturias Centrico
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.4Good - What previous guests thought, 127 reviewsLocated in Santa Cruz de la Sierra, a 9-minute walk from Sacred Art Museum, Ex Hotel Asturias Centrico has accommodations with an outdoor swimming pool, free private parking, a garden and a terrace.
From $23 per nightResidencial IKANDIRE ll
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.4Good - What previous guests thought, 284 reviewsResidencial IKANDIRE ll is located in Santa Cruz de la Sierra, a 17-minute walk from Metropolitan Cathedral and 0.8 miles from Güembé Biocentre and Guazú Ivaga Park.
From $14 per nightHotel Casa Blanca
Hotel in La Playa BejaranoNo credit card neededHotel Casa Blanca is a 5-star property located in La Playa Bejarano.
From $33 per nightHotel Libertador
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.1Good - What previous guests thought, 10 reviewsLocated within a 4-minute walk of Metropolitan Cathedral and 1.6 miles of Gabriel Rene Moreno Autonomous University, Hotel Libertador provides rooms in Santa Cruz de la Sierra.
From $45 per nightHotel el Marqués
Hotel in VallegrandeNo credit card neededScored out of 10, guest rating 7.8Good - What previous guests thought, 14 reviewsFeaturing a terrace, Hotel el Marqués is located in Vallegrande. Among the facilities of this property are a restaurant, room service and a 24-hour front desk, along with free WiFi throughout the...
From $38.50 per nightHotel La Casona de Don Pepe
Hotel in RoboréNo credit card neededScored out of 10, guest rating 8.0Very Good - What previous guests thought, 2 reviewsLocated in Roboré, Hotel La Casona de Don Pepe offers 2-star accommodations with an outdoor swimming pool, a garden and a terrace.
From $58 per nightGaman Hotel Glamping
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.3Good - What previous guests thought, 8 reviewsLocated in Santa Cruz de la Sierra, within a 14-minute walk of Güembé Biocentre and Guazú Ivaga Park and one mile of 24th of September Metropolitan Plaza, Gaman Hotel Glamping provides accommodations...
From $40 per night
FAQs about hotels in Santa Cruz Region
See reviews by guests who stayed at hotels in Santa Cruz Region
- From $63.28 per nightScored out of 10, guest rating 7.8Good - What previous guests thought, 1,144 reviewsThe central location is great -- especially since I was in Santa Cruz for only a short stay. The hotel was very clean. The staff were friendly, kind, and knowledgeable. (I mostly dealt with Santiago at the front desk but all employees were helpful.) I was surprised by the free breakfast (I think the Booking.com description says the hotel doesn't provide meals) with lots of in-season fruit! And I didn't realize there is a pool, which looked well maintained.Guest review byLindaUnited States
- From $134.10 per nightScored out of 10, guest rating 8.8Excellent - What previous guests thought, 487 reviewsEverything. Spacious room, modern bathroom, nice tropical atmosphere (peacocks and a turtle walking around) very friendly staff. We especially liked the poolside restaurant, which had good cocktails, very tasty buffets (brunch on Saturday, grill on Sunday), and works 24h. Spa and pool areas very nice, too. The location is great, very close (walking) to restaurants, malls and only 15min by car to the central square.Guest review bySebastianChile
- From $105 per nightScored out of 10, guest rating 9.4Wonderful - What previous guests thought, 190 reviewsEl Pueblito is a representation of a small town, each room representing parts if the town with exquisite decoration. You have a carpentry, bank, florist, artist’ house, chapel, etc… the view is magnificent. El Pueblito is a nice quiet place to relax. The food is very good as well. The family that owns and runs the hotel is very attentive and warm. 100% recommended!Guest review byMaria CeciliaBolivia
- From $44 per nightScored out of 10, guest rating 8.0Very Good - What previous guests thought, 402 reviewsClean, comfortable, perfectly adequate for my one-night stay before heading on to Samaipata. Trufis leave from a block away (staff don’t seem to know about this, look for “trufis a Samaipata” on google maps). Several options for breakfast.Guest review byJessicaUnited States
- From $120 per nightScored out of 10, guest rating 7.5Good - What previous guests thought, 556 reviewsThe location was great! Facilities were clean and beautiful. Staff was lovely. Loved this place, definitely will stay here again!Guest review byRafaelaBolivia
- From $65 per nightScored out of 10, guest rating 9.0Wonderful - What previous guests thought, 91 reviewsExcellent location, beautiful hotel and room. Wonderful breakfast, wonderful staff. Highly recommend!Guest review byDavidUnited States
- From $148.50 per nightScored out of 10, guest rating 9.3Wonderful - What previous guests thought, 218 reviewsEvery time I need a short stay in Santa Cruz I choose this hotel. Everything is cleanGuest review byivanUnited States
- From $69.90 per nightScored out of 10, guest rating 7.5Good - What previous guests thought, 188 reviewsIt was nice, the location was very good. Sad that I couldn’t try the pool.Guest review byCarolaSweden
- From $66.89 per nightScored out of 10, guest rating 8.0Very Good - What previous guests thought, 388 reviewsGreat breakfast. Great hotel. Great priceGuest review bymaureenUnited States
- From $61.83 per nightScored out of 10, guest rating 8.3Very Good - What previous guests thought, 318 reviewssafe neighborhood and clean facilitiesGuest review byRaulUnited States
Planning a trip? Get inspired by reviews of cities in Santa Cruz Region
- 6.0
It's a city with not much to offer.
It's a city with not much to offer. You're better off in La Paz, where the views are nicer, the scenery is just better. But you're really much better off in the more rural places, in the mountains, by the lakes and away from the cities.Guest review byOgnyanUnited Kingdom - 8.0
Santa Cruz de la Sierra is an interesting city with a busy...
Santa Cruz de la Sierra is an interesting city with a busy and parcely old part downtown. You find museums, the main plaza with the cathedral, shops for everyone, big restaurants and small places who sell delicious local food. Also thera are some modern shopping malls as also black markets where you find everything you might need for living. Cultural events are offered and some really nice places with abundant semi-tropical vegetation as well as places with a lake to swim and hotels. You can take a taxi or go by bus to almost every place you like, in general it is very safe, only in the outskirts you should be more careful and maybe not go there at nigt. Always take your purse with important things in front of you - just in case! I certainly recommend Santa Cruz for a visit! A little bit outside there are the sanddunes and the botanical garden and other places like the Chiquitania, also very worth visiting!Guest review byCorneliaGermany - 8.0
Friendly people (is famous for its hospitality).
Friendly people (is famous for its hospitality). Is the most productive area of the country, you can find everything you expect of a big city. I like my staying and I will be back with more time and better organized agenda. Given the size of the city and the weather (mostly humid and hot) a car is necessary to visit properly Santa Cruz.Guest review byFlavio David Y.Bolivia