In partnership with
www.qyer.com

Search hotels in Santa Cruz Region, Bolivia

Enter your dates and choose from 914 hotels and other places to stay

Check out these popular cities in Santa Cruz Region

Stay in Santa Cruz Region's best hotels!

Show hotels on map

Filter by:

Star Rating

Review score

Cosmopolitano Hotel Boutique

Hotel in Santa Cruz de la Sierra

Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical center of Santa Cruz de la Sierra. Guests can enjoy the on-site bar.

I
Ikenna
From
Trinidad and Tobago
Service was impeccable. We had to leave at 4:00 am in the morning to catch our flight and they made a full breakfast for us before we left.
Scored out of 10, guest rating 9.1
Wonderful - What previous guests thought, 1,112 reviews
Location 9.3
Price from
$84.23
1 night, 2 adults
Check availability

TRYP by Wyndham Santa Cruz

Hotel in Santa Cruz de la Sierra

Located in Santa Cruz de la Sierra, a 19-minute walk from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz has accommodations with an outdoor swimming pool, free private parking,...

M
Muhamed
From
Bolivia
Amazing and modern hotel, with a nice breakfast, friendly and helpful staff and a great location too
Scored out of 10, guest rating 9.0
Wonderful - What previous guests thought, 592 reviews
Location 9.5
Price from
$63.20
1 night, 2 adults
Check availability

YVY CASA HOTEL

Hotel in Samaipata

Located in Samaipata, 6.1 miles from Samaipata Fort, YVY CASA HOTEL provides accommodations with a garden, free private parking and a terrace.

R
Rosanna
From
United Kingdom
We loved waking up to the sound of birds and to a beautiful green view. Helen was a really lovely host who was happy to give us recommendations for the local area - all in English which was appreciated as we only speak basic spanish. The breakfast was also amazing, and we loved reading in the hammocks under the trees while listening to the birdlife. The hotel is only a short walk from the main town but far away enough to be immersed in nature. Our room and bed were very comfortable. Everything was so perfect!
Scored out of 10, guest rating 9.4
Wonderful - What previous guests thought, 444 reviews
Location 9.0
Price from
$55
1 night, 2 adults
Check availability

Marriott Santa Cruz de la Sierra Hotel

Hotel in Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness center, a shared lounge and terrace in Santa Cruz de la Sierra.

d
douglas
From
United States
Great breakfast, exceptional, very friendly staff
Scored out of 10, guest rating 9.1
Wonderful - What previous guests thought, 340 reviews
Location 9.1
Price from
$130.38
1 night, 2 adults
Check availability

El Pueblito Hotel Boutique

Hotel in Samaipata

Located in Samaipata, 7 miles from Samaipata Fort, El Pueblito Hotel Boutique has accommodations with an outdoor swimming pool, free private parking, a garden and a shared lounge.

M
Mollie
From
Brazil
We loved the charm, comfort and friendly, helpful staff.
Scored out of 10, guest rating 9.4
Wonderful - What previous guests thought, 188 reviews
Location 8.9
Price from
$93.45
1 night, 2 adults
Check availability

Hotel Cortez

Hotel in Santa Cruz de la Sierra

Boasting an outdoor swimming pool, gym and spa facilities, Hotel Cortez has chic and spacious rooms in Santa Cruz de la Sierra. Free WiFi access is available.

i
ivan
From
United States
Every time I need a short stay in Santa Cruz I choose this hotel. Everything is clean
Scored out of 10, guest rating 9.3
Wonderful - What previous guests thought, 219 reviews
Location 9.2
Price from
$148.50
1 night, 2 adults
Check availability

Hotel By Armonía Santa Cruz

Hotel in Santa Cruz de la Sierra

Located in Santa Cruz de la Sierra, a 19-minute walk from Güembé Biocentre and Guazú Ivaga Park, Hotel By Armonía Santa Cruz has accommodations with an outdoor swimming pool, free private parking, a...

B
Bill
From
United States
Pick up at the airport at 2:00 AM - no extra charge. We enjoyed b'fast in the morning - very gracious service in a lovely outdoor setting. They let us leave our bags for an extra night. Thanks!
Scored out of 10, guest rating 9.3
Wonderful - What previous guests thought, 92 reviews
Location 8.6
Price from
$65.03
1 night, 2 adults
Check availability

La Vida es Bella

Hotel in Samaipata

Located in Samaipata, 5.6 miles from Samaipata Fort, La Vida es Bella provides accommodations with a garden, free private parking, a shared lounge and a terrace.

Scored out of 10, guest rating 9.0
Wonderful - What previous guests thought, 88 reviews
Location 8.4
Price from
$65
1 night, 2 adults
Check availability

Lido Hotel

Hotel in Santa Cruz de la Sierra

Lido Hotel has accommodations in Santa Cruz de la Sierra near Metropolitan Cathedral and Gabriel Rene Moreno Autonomous University.

J
Josee
From
United States
The staff was extraordinarily helpful considerate and kind. The food at their restaurant was very good in taste and in value. The location is minutes away from the main square. We will be back on our way out of the country.
Scored out of 10, guest rating 8.6
Excellent - What previous guests thought, 100 reviews
Location 8.9
Price from
$44.13
1 night, 2 adults
Check availability

Chairu Eco Hotel

Hotel in Santa Cruz de la Sierra

Chairu Eco Hotel features an outdoor swimming pool, shared lounge, a terrace and restaurant in Santa Cruz de la Sierra.

M
Malitay
From
Bolivia
Breakfast was great, good hours and nice staff! I would suggest adding more options, preferably meat like bacon, sausage, etc.
Scored out of 10, guest rating 8.9
Excellent - What previous guests thought, 800 reviews
Location 9.1
Price from
$75
1 night, 2 adults
Check availability
See all 914 hotels in Santa Cruz Region

Most-booked hotels in Santa Cruz Region in the past month

See all

Santa Cruz Region's best hotels with breakfast

  • Scored out of 10, guest rating 8.9
    Excellent - What previous guests thought, 256 reviews

    Located in Santa Cruz de la Sierra, a 15-minute walk from Arenal Park, ibis Santa Cruz de la Sierra provides accommodations with a shared lounge, free private parking, a restaurant and a bar.

    From $72 per night
  • Scored out of 10, guest rating 8.7
    Excellent - What previous guests thought, 181 reviews

    Located in Santa Cruz de la Sierra, 2.2 miles from Gabriel Rene Moreno Autonomous University, Novotel Santa Cruz De La Sierra has accommodations with an outdoor swimming pool, free private parking, a...

    From $154 per night
  • Scored out of 10, guest rating 8.9
    Excellent - What previous guests thought, 800 reviews

    Chairu Eco Hotel features an outdoor swimming pool, shared lounge, a terrace and restaurant in Santa Cruz de la Sierra.

    From $80 per night
  • Scored out of 10, guest rating 8.9
    Excellent - What previous guests thought, 286 reviews

    Located in Santa Cruz de la Sierra, 2.8 miles from Gabriel Rene Moreno Autonomous University, Swissotel Santa Cruz de La Sierra has accommodations with an outdoor swimming pool, free private parking,...

    From $148 per night
  • Scored out of 10, guest rating 8.0
    Very Good - What previous guests thought, 304 reviews

    Located in Santa Cruz de la Sierra, 1.4 miles from Gabriel Rene Moreno Autonomous University, Delfines Collection Hotel by Mercure provides accommodations with an outdoor swimming pool, free private...

    From $62.57 per night
  • Scored out of 10, guest rating 8.7
    Excellent - What previous guests thought, 362 reviews

    Located in Santa Cruz de la Sierra, 1.3 miles from Gabriel Rene Moreno Autonomous University, Hampton by Hilton Santa Cruz provides accommodations with a fitness center, free private parking, a garden...

  • Scored out of 10, guest rating 8.7
    Excellent - What previous guests thought, 161 reviews

    Featuring 5-star accommodations, Mai Suites Apart Hotel is located in Santa Cruz de la Sierra, 1.2 miles from Gabriel Rene Moreno Autonomous University and 2.6 miles from Arenal Park.

    From $85 per night
  • Scored out of 10, guest rating 8.0
    Very Good - What previous guests thought, 390 reviews

    Located in the commercial district of Equipetrol, this property offers accommodations with free WiFi access in Santa Cruz de la Sierra.

    From $66.89 per night

Budget hotels in Santa Cruz Region

  • Scored out of 10, guest rating 8.5
    Very Good - What previous guests thought, 244 reviews

    Located in Santa Cruz de la Sierra, 1.2 miles from Gabriel Rene Moreno Autonomous University, Hotel Sirari By Regina has accommodations with an outdoor swimming pool, free private parking, a fitness...

    From $95 per night
  • Scored out of 10, guest rating 8.3
    Very Good - What previous guests thought, 319 reviews

    The LP Santa Cruz Hotel is a 3-star hotel located few yards from Blacutt Square in central Santa Cruz. It offers rooms with cable TV, a mini-bar and free Wi-Fi.

    From $61.83 per night
  • Scored out of 10, guest rating 8.8
    Excellent - What previous guests thought, 81 reviews

    Located in Santa Cruz de la Sierra, 1.9 miles from Güembé Biocentre and Guazú Ivaga Park, Hotel Maywa has accommodations with a fitness center, free private parking, a shared lounge and a terrace.

    From $48.45 per night
  • Scored out of 10, guest rating 7.9
    Good - What previous guests thought, 1,132 reviews

    Featuring an outdoor pool, La Siesta Hotel offers accommodations in Santa Cruz de la Sierra. Free WiFi access is available.

    From $63.28 per night
  • Scored out of 10, guest rating 6.4
    Pleasant - What previous guests thought, 268 reviews

    Located in Santa Cruz de la Sierra, within 8.9 miles of Arenal Park and 9.1 miles of 24th of September Metropolitan Plaza, Hotel Viru Viru II provides accommodations with a fitness center and free...

    From $42.50 per night
  • Scored out of 10, guest rating 7.5
    Good - What previous guests thought, 187 reviews

    Featuring a swimming pool, a fitness center and a restaurant, Hotel Arenal offers rooms with free Wi-Fi and flat-screen TVs in Santa Cruz de la Sierra. Free parking is provided.

    From $69.90 per night
  • Scored out of 10, guest rating 6.5
    Pleasant - What previous guests thought, 6 reviews

    Mansión By Hotel Casablanca is a 2-star property located in Samaipata. Samaipata Fort is 5.7 miles from the hotel.

    From $67.32 per night
  • Scored out of 10, guest rating 8.0
    Very Good - What previous guests thought, 11 reviews

    Hotel Boutique Plaza24 has a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a shared kitchen and room service.

    From $60 per night

Hotels in Santa Cruz Region you can book without a credit card

  • Scored out of 10, guest rating 8.4
    Very Good - What previous guests thought, 17 reviews

    Featuring a terrace and barbecue facilities, LA CASONA Hotel Boutique is located in Camiri.

    From $40 per night
  • Scored out of 10, guest rating 7.3
    Good - What previous guests thought, 132 reviews

    Located in Santa Cruz de la Sierra, a 9-minute walk from Sacred Art Museum, Ex Hotel Asturias Centrico has accommodations with an outdoor swimming pool, free private parking, a garden and a terrace.

    From $29 per night
  • Scored out of 10, guest rating 7.3
    Good - What previous guests thought, 281 reviews

    Residencial IKANDIRE ll is located in Santa Cruz de la Sierra, a 17-minute walk from Metropolitan Cathedral and 0.8 miles from Güembé Biocentre and Guazú Ivaga Park.

    From $14.50 per night

  • Hotel Casa Blanca is a 5-star property located in La Playa Bejarano.

    From $33 per night
  • Scored out of 10, guest rating 7.1
    Good - What previous guests thought, 10 reviews

    Located within a 4-minute walk of Metropolitan Cathedral and 1.6 miles of Gabriel Rene Moreno Autonomous University, Hotel Libertador provides rooms in Santa Cruz de la Sierra.

  • Scored out of 10, guest rating 7.8
    Good - What previous guests thought, 14 reviews

    Featuring a terrace, Hotel el Marqués is located in Vallegrande. Among the facilities of this property are a restaurant, room service and a 24-hour front desk, along with free WiFi throughout the...

    From $38.50 per night
  • Scored out of 10, guest rating 8.0
    Very Good - What previous guests thought, 2 reviews

    Located in Roboré, Hotel La Casona de Don Pepe offers 2-star accommodations with an outdoor swimming pool, a garden and a terrace.

    From $58 per night
  • Scored out of 10, guest rating 7.5
    Good - What previous guests thought, 9 reviews

    Located in Santa Cruz de la Sierra, within a 14-minute walk of Güembé Biocentre and Guazú Ivaga Park and one mile of 24th of September Metropolitan Plaza, Gaman Hotel Glamping provides accommodations...

    From $37 per night

FAQs about hotels in Santa Cruz Region

See reviews by guests who stayed at hotels in Santa Cruz Region

See all

  • La Siesta Hotel

    Santa Cruz de la Sierra
    From $63.28 per night
    Scored out of 10, guest rating 7.9
    Good - What previous guests thought, 1,132 reviews
    The central location is great -- especially since I was in Santa Cruz for only a short stay. The hotel was very clean. The staff were friendly, kind, and knowledgeable. (I mostly dealt with Santiago at the front desk but all employees were helpful.) I was surprised by the free breakfast (I think the Booking.com description says the hotel doesn't provide meals) with lots of in-season fruit! And I didn't realize there is a pool, which looked well maintained.
    Guest review by
    Linda
    United States

  • Prince Hotel

    Santa Cruz de la Sierra
    From $44 per night
    Scored out of 10, guest rating 8.0
    Very Good - What previous guests thought, 399 reviews
    Clean, comfortable, perfectly adequate for my one-night stay before heading on to Samaipata. Trufis leave from a block away (staff don’t seem to know about this, look for “trufis a Samaipata” on google maps). Several options for breakfast.
    Guest review by
    Jessica
    United States

  • Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

    Santa Cruz de la Sierra
    From $170.10 per night
    Scored out of 10, guest rating 8.8
    Excellent - What previous guests thought, 491 reviews
    The combination of Nature (magnificent gardens, trees, birds) and Art (numerous excellent paintings and sculpture from local artists). Colorful and peaceful.
    Guest review by
    Claudio
    United States

  • Sun Hotel

    Santa Cruz de la Sierra
    From $120 per night
    Scored out of 10, guest rating 7.5
    Good - What previous guests thought, 552 reviews
    The location was great! Facilities were clean and beautiful. Staff was lovely. Loved this place, definitely will stay here again!
    Guest review by
    Rafaela
    Bolivia

  • Hotel Cortez

    Santa Cruz de la Sierra
    Scored out of 10, guest rating 9.3
    Wonderful - What previous guests thought, 219 reviews
    Every time I need a short stay in Santa Cruz I choose this hotel. Everything is clean
    Guest review by
    ivan
    United States

  • Hotel Arenal

    Santa Cruz de la Sierra
    From $69.90 per night
    Scored out of 10, guest rating 7.5
    Good - What previous guests thought, 187 reviews
    It was nice, the location was very good. Sad that I couldn’t try the pool.
    Guest review by
    Carola
    Sweden

  • El Pueblito Hotel Boutique

    Samaipata
    From $105 per night
    Scored out of 10, guest rating 9.4
    Wonderful - What previous guests thought, 188 reviews
    We loved the charm, comfort and friendly, helpful staff.
    Guest review by
    Mollie
    Brazil

  • LP Equipetrol

    Santa Cruz de la Sierra
    From $66.89 per night
    Scored out of 10, guest rating 8.0
    Very Good - What previous guests thought, 390 reviews
    Great breakfast. Great hotel. Great price
    Guest review by
    maureen
    United States

  • Hotel LP Santa Cruz Centro

    Santa Cruz de la Sierra
    From $61.83 per night
    Scored out of 10, guest rating 8.3
    Very Good - What previous guests thought, 319 reviews
    safe neighborhood and clean facilities
    Guest review by
    Raul
    United States

Planning a trip? Get inspired by reviews of cities in Santa Cruz Region

  • 6.0

    It's a city with not much to offer.

    It's a city with not much to offer. You're better off in La Paz, where the views are nicer, the scenery is just better. But you're really much better off in the more rural places, in the mountains, by the lakes and away from the cities.
    Guest review by
    Ognyan
    United Kingdom
  • 8.0

    Santa Cruz de la Sierra is an interesting city with a busy...

    Santa Cruz de la Sierra is an interesting city with a busy and parcely old part downtown. You find museums, the main plaza with the cathedral, shops for everyone, big restaurants and small places who sell delicious local food. Also thera are some modern shopping malls as also black markets where you find everything you might need for living. Cultural events are offered and some really nice places with abundant semi-tropical vegetation as well as places with a lake to swim and hotels. You can take a taxi or go by bus to almost every place you like, in general it is very safe, only in the outskirts you should be more careful and maybe not go there at nigt. Always take your purse with important things in front of you - just in case! I certainly recommend Santa Cruz for a visit! A little bit outside there are the sanddunes and the botanical garden and other places like the Chiquitania, also very worth visiting!
    Guest review by
    Cornelia
    Germany
  • 8.0

    Friendly people (is famous for its hospitality).

    Friendly people (is famous for its hospitality). Is the most productive area of the country, you can find everything you expect of a big city. I like my staying and I will be back with more time and better organized agenda. Given the size of the city and the weather (mostly humid and hot) a car is necessary to visit properly Santa Cruz.
    Guest review by
    Flavio David Y.
    Bolivia

Research, refine, and make plans for your whole trip

Cheap vacations in Santa Cruz de la Sierra

Plan everything you need for your vacation in one place – from flights and stays to tours and activities

Flights from New York to Santa Cruz de la Sierra

Find and compare prices for popular flight routes.

Car rental near Viru Viru International Airport

Pick up your rental car as soon as you land.

Hotels in Santa Cruz de la Sierra

A popular choice with guests visiting Santa Cruz Region.

Flights to Santa Cruz Region

Getting to Santa Cruz Region just got easier!

Hotels on Isla del Sol Island

Discover another popular destination in Bolivia.

Hotels in Uyuni Salt Flat

Hit the road and make the most of your trip by discovering another popular destination in Bolivia.

Hotels near Viru Viru International Airport

Perfect for a late arrival or early departure.

Hotels in Bolivia

Set off to explore the whole country.
gogless