Search hotels in Santa Cruz Region, Bolivia
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Check out these popular cities in Santa Cruz Region
Santa Cruz de la Sierra
1021 hotelsSamaipata
65 hotelsIsla del Mono
3 hotelsEl Pari
40 hotelsLa Playa Bejarano
42 hotelsHamacas
9 hotelsCamiri
2 hotelsBuena Vista
12 hotelsVila El Carmen
5 hotelsVallegrande
5 hotels
Stay in Santa Cruz Region's best hotels!
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Cosmopolitano Hotel Boutique
Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical center of Santa Cruz de la Sierra. Guests can enjoy the on-site bar.

TRYP by Wyndham Santa Cruz
Located in Santa Cruz de la Sierra, a 19-minute walk from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz has accommodations with an outdoor swimming pool, free private parking,...

YVY CASA HOTEL
Located in Samaipata, 6.1 miles from Samaipata Fort, YVY CASA HOTEL provides accommodations with a garden, free private parking and a terrace.

Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness center, a shared lounge and terrace in Santa Cruz de la Sierra.

El Pueblito Hotel Boutique
Located in Samaipata, 7 miles from Samaipata Fort, El Pueblito Hotel Boutique has accommodations with an outdoor swimming pool, free private parking, a garden and a shared lounge.

Hotel Cortez
Boasting an outdoor swimming pool, gym and spa facilities, Hotel Cortez has chic and spacious rooms in Santa Cruz de la Sierra. Free WiFi access is available.

Chairu Eco Hotel
Chairu Eco Hotel features an outdoor swimming pool, shared lounge, a terrace and restaurant in Santa Cruz de la Sierra.

Hampton by Hilton Santa Cruz
Located in Santa Cruz de la Sierra, 1.3 miles from Gabriel Rene Moreno Autonomous University, Hampton by Hilton Santa Cruz provides accommodations with a fitness center, free private parking, a garden...

Mai Suites Apart Hotel
Featuring 5-star accommodations, Mai Suites Apart Hotel is located in Santa Cruz de la Sierra, 1.2 miles from Gabriel Rene Moreno Autonomous University and 2.6 miles from Arenal Park.

LP Equipetrol
Located in the commercial district of Equipetrol, this property offers accommodations with free WiFi access in Santa Cruz de la Sierra.

Most-booked hotels in Santa Cruz Region in the past month
Popular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.9Excellent - What previous guests thought, 245 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 9.1Wonderful - What previous guests thought, 1,111 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.9Excellent - What previous guests thought, 797 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.7Excellent - What previous guests thought, 367 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.9Good - What previous guests thought, 1,142 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 9.0Wonderful - What previous guests thought, 594 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.7Good - What previous guests thought, 215 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.5Good - What previous guests thought, 187 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.8Excellent - What previous guests thought, 488 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.5Good - What previous guests thought, 556 reviews
Santa Cruz Region's best hotels with breakfast
ibis Santa Cruz de la Sierra
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.9Excellent - What previous guests thought, 245 reviewsLocated in Santa Cruz de la Sierra, a 15-minute walk from Arenal Park, ibis Santa Cruz de la Sierra provides accommodations with a shared lounge, free private parking, a restaurant and a bar.
From $72 per nightNovotel Santa Cruz De La Sierra
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.7Excellent - What previous guests thought, 181 reviewsLocated in Santa Cruz de la Sierra, 2.2 miles from Gabriel Rene Moreno Autonomous University, Novotel Santa Cruz De La Sierra has accommodations with an outdoor swimming pool, free private parking, a...
From $105 per nightChairu Eco Hotel
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.9Excellent - What previous guests thought, 797 reviewsChairu Eco Hotel features an outdoor swimming pool, shared lounge, a terrace and restaurant in Santa Cruz de la Sierra.
From $80 per nightSwissotel Santa Cruz de La Sierra
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.9Excellent - What previous guests thought, 289 reviewsLocated in Santa Cruz de la Sierra, 2.8 miles from Gabriel Rene Moreno Autonomous University, Swissotel Santa Cruz de La Sierra has accommodations with an outdoor swimming pool, free private parking,...
From $148 per nightDelfines Collection Hotel by Mercure
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.0Very Good - What previous guests thought, 303 reviewsLocated in Santa Cruz de la Sierra, 1.4 miles from Gabriel Rene Moreno Autonomous University, Delfines Collection Hotel by Mercure provides accommodations with an outdoor swimming pool, free private...
From $62.57 per nightHampton by Hilton Santa Cruz
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.7Excellent - What previous guests thought, 367 reviewsLocated in Santa Cruz de la Sierra, 1.3 miles from Gabriel Rene Moreno Autonomous University, Hampton by Hilton Santa Cruz provides accommodations with a fitness center, free private parking, a garden...
From $108.43 per nightMai Suites Apart Hotel
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.7Excellent - What previous guests thought, 162 reviewsFeaturing 5-star accommodations, Mai Suites Apart Hotel is located in Santa Cruz de la Sierra, 1.2 miles from Gabriel Rene Moreno Autonomous University and 2.6 miles from Arenal Park.
From $85 per nightLP Equipetrol
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.0Very Good - What previous guests thought, 388 reviewsLocated in the commercial district of Equipetrol, this property offers accommodations with free WiFi access in Santa Cruz de la Sierra.
From $66.89 per night
Budget hotels in Santa Cruz Region
HOTEL OSHO
Hotel in Santa Cruz de la SierraCheap hotelScored out of 10, guest rating 8.3Very Good - What previous guests thought, 645 reviewsLocated in Santa Cruz de la Sierra, a 4-minute walk from Güembé Biocentre and Guazú Ivaga Park, HOTEL OSHO has accommodations with an outdoor swimming pool, free private parking, a fitness center and...
From $54 per night- Scored out of 10, guest rating 8.5Very Good - What previous guests thought, 250 reviews
Located in Santa Cruz de la Sierra, 1.2 miles from Gabriel Rene Moreno Autonomous University, Hotel Sirari By Regina has accommodations with an outdoor swimming pool, free private parking, a fitness...
From $95 per night - Scored out of 10, guest rating 8.3Very Good - What previous guests thought, 318 reviews
The LP Santa Cruz Hotel is a 3-star hotel located few yards from Blacutt Square in central Santa Cruz. It offers rooms with cable TV, a mini-bar and free Wi-Fi.
From $61.83 per night Hotel Maywa
Hotel in Santa Cruz de la SierraCheap hotelScored out of 10, guest rating 8.8Excellent - What previous guests thought, 80 reviewsLocated in Santa Cruz de la Sierra, 1.9 miles from Güembé Biocentre and Guazú Ivaga Park, Hotel Maywa has accommodations with a fitness center, free private parking, a shared lounge and a terrace.
From $48.45 per night- Scored out of 10, guest rating 7.9Good - What previous guests thought, 1,142 reviews
Featuring an outdoor pool, La Siesta Hotel offers accommodations in Santa Cruz de la Sierra. Free WiFi access is available.
From $63.28 per night - Scored out of 10, guest rating 6.3Pleasant - What previous guests thought, 268 reviews
Located in Santa Cruz de la Sierra, within 8.9 miles of Arenal Park and 9.1 miles of 24th of September Metropolitan Plaza, Hotel Viru Viru II provides accommodations with a fitness center and free...
From $42.50 per night Hotel Arenal
Hotel in Santa Cruz de la SierraCheap hotelScored out of 10, guest rating 7.5Good - What previous guests thought, 187 reviewsFeaturing a swimming pool, a fitness center and a restaurant, Hotel Arenal offers rooms with free Wi-Fi and flat-screen TVs in Santa Cruz de la Sierra. Free parking is provided.
From $69.90 per night- Scored out of 10, guest rating 4.8Disappointing - What previous guests thought, 4 reviews
Mansión By Hotel Casablanca is a 2-star property located in Samaipata. Samaipata Fort is 5.7 miles from the hotel.
From $42.90 per night
Hotels in Santa Cruz Region you can book without a credit card
LA CASONA Hotel Boutique
Hotel in CamiriNo credit card neededScored out of 10, guest rating 8.4Very Good - What previous guests thought, 17 reviewsFeaturing a terrace and barbecue facilities, LA CASONA Hotel Boutique is located in Camiri.
From $40 per nightEx Hotel Asturias Centrico
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.4Good - What previous guests thought, 128 reviewsLocated in Santa Cruz de la Sierra, a 9-minute walk from Sacred Art Museum, Ex Hotel Asturias Centrico has accommodations with an outdoor swimming pool, free private parking, a garden and a terrace.
From $23 per nightResidencial IKANDIRE ll
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.4Good - What previous guests thought, 283 reviewsResidencial IKANDIRE ll is located in Santa Cruz de la Sierra, a 17-minute walk from Metropolitan Cathedral and 0.8 miles from Güembé Biocentre and Guazú Ivaga Park.
From $14 per nightHotel Casa Blanca
Hotel in La Playa BejaranoNo credit card neededHotel Casa Blanca is a 5-star property located in La Playa Bejarano.
From $33 per nightHotel Boutique Plaza24
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.8Good - What previous guests thought, 10 reviewsHotel Boutique Plaza24 has a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a shared kitchen and room service.
From $60 per nightHotel Libertador
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.1Good - What previous guests thought, 10 reviewsLocated within a 4-minute walk of Metropolitan Cathedral and 1.6 miles of Gabriel Rene Moreno Autonomous University, Hotel Libertador provides rooms in Santa Cruz de la Sierra.
From $45 per nightHotel el Marqués
Hotel in VallegrandeNo credit card neededScored out of 10, guest rating 7.8Good - What previous guests thought, 14 reviewsFeaturing a terrace, Hotel el Marqués is located in Vallegrande. Among the facilities of this property are a restaurant, room service and a 24-hour front desk, along with free WiFi throughout the...
From $38.50 per nightHotel La Casona de Don Pepe
Hotel in RoboréNo credit card neededScored out of 10, guest rating 8.0Very Good - What previous guests thought, 2 reviewsLocated in Roboré, Hotel La Casona de Don Pepe offers 2-star accommodations with an outdoor swimming pool, a garden and a terrace.
From $58 per night
FAQs about hotels in Santa Cruz Region
See reviews by guests who stayed at hotels in Santa Cruz Region
- From $105 per nightScored out of 10, guest rating 9.4Wonderful - What previous guests thought, 190 reviewsStaff was lovely and helpful. They even brought us a forgotten item down to Santa Cruz. It’s a bit of a trek—or short taxi— up the hill but the views, clean air and pool make it worth it. Plus each room is lovingly decorated and unique.Guest review byNaomiUnited States
- From $120 per nightScored out of 10, guest rating 7.5Good - What previous guests thought, 556 reviewsThe location was great! Facilities were clean and beautiful. Staff was lovely. Loved this place, definitely will stay here again!Guest review byRafaelaBolivia
- From $65 per nightScored out of 10, guest rating 9.0Wonderful - What previous guests thought, 90 reviewsExcellent location, beautiful hotel and room. Wonderful breakfast, wonderful staff. Highly recommend!Guest review byDavidUnited States
- From $63.28 per nightScored out of 10, guest rating 7.9Good - What previous guests thought, 1,142 reviewsGreat location. It´s close to the commercial district. The staff is very polite and kind.Guest review byCesar FazzolariBrazil
- From $148.50 per nightScored out of 10, guest rating 9.3Wonderful - What previous guests thought, 219 reviewsEvery time I need a short stay in Santa Cruz I choose this hotel. Everything is cleanGuest review byivanUnited States
- From $69.90 per nightScored out of 10, guest rating 7.5Good - What previous guests thought, 187 reviewsIt was nice, the location was very good. Sad that I couldn’t try the pool.Guest review byCarolaSweden
- From $66.89 per nightScored out of 10, guest rating 8.0Very Good - What previous guests thought, 388 reviewsGreat breakfast. Great hotel. Great priceGuest review bymaureenUnited States
- From $61.83 per nightScored out of 10, guest rating 8.3Very Good - What previous guests thought, 318 reviewssafe neighborhood and clean facilitiesGuest review byRaulUnited States
- From $134.10 per nightScored out of 10, guest rating 8.8Excellent - What previous guests thought, 488 reviewsVery clean. Excellent breakfast.Guest review byIngridBolivia
- From $44 per nightScored out of 10, guest rating 8.0Very Good - What previous guests thought, 402 reviewsThey turned the sauna on for us.Guest review byGalenBolivia
Planning a trip? Get inspired by reviews of cities in Santa Cruz Region
- 6.0
It's a city with not much to offer.
It's a city with not much to offer. You're better off in La Paz, where the views are nicer, the scenery is just better. But you're really much better off in the more rural places, in the mountains, by the lakes and away from the cities.Guest review byOgnyanUnited Kingdom - 8.0
Santa Cruz de la Sierra is an interesting city with a busy...
Santa Cruz de la Sierra is an interesting city with a busy and parcely old part downtown. You find museums, the main plaza with the cathedral, shops for everyone, big restaurants and small places who sell delicious local food. Also thera are some modern shopping malls as also black markets where you find everything you might need for living. Cultural events are offered and some really nice places with abundant semi-tropical vegetation as well as places with a lake to swim and hotels. You can take a taxi or go by bus to almost every place you like, in general it is very safe, only in the outskirts you should be more careful and maybe not go there at nigt. Always take your purse with important things in front of you - just in case! I certainly recommend Santa Cruz for a visit! A little bit outside there are the sanddunes and the botanical garden and other places like the Chiquitania, also very worth visiting!Guest review byCorneliaGermany - 8.0
Friendly people (is famous for its hospitality).
Friendly people (is famous for its hospitality). Is the most productive area of the country, you can find everything you expect of a big city. I like my staying and I will be back with more time and better organized agenda. Given the size of the city and the weather (mostly humid and hot) a car is necessary to visit properly Santa Cruz.Guest review byFlavio David Y.Bolivia