Built in 1790, the James Pharmacy originally served as the general store for the Humphrey Pratt Tavern. General Lafayette made a purchase there when he returned in 1824 to America on a triumphal tour and visit with old Revolutionary War friends. In 1895 Peter Lane and his wife and Bertha moved to Old Saybrook and rented the building. He - one of the first African-American pharmacists in CT – established the town’s first pharmacy. A soda fountain was added in 1896. Miss Anna Louise James was Peter Lane’s niece. In 1902, when Anna was sixteen years old, she worked under Uncle Peter’s tutelage. Anna became the first African American woman to graduate from the Brooklyn College of Pharmacy and the first African American female pharmacist in CT. When Peter was called away to fight in World War I, in 1917, he left the care of what was then the Lane Pharmacy with his sister-in-law, Anna Louise James. She took over the business, eventually renaming it James Pharmacy. Anna’s niece Ann began writing short stories while working in her father’s store. She went on to publish six books; her The Street sold more than a million copies. In 2017, the James Pharmacy was lovingly converted into a

The James Pharmacy Bed and Breakfast is your base for adventure. With scenic beaches, miles of coastline, pretty coves, the mouth of the CT River, and two lighthouses, there is a lot to see. The James is located in the historic district less than 1,000 feet from the Main Street with its quaint shops and cafes. Bike or drive (be sure to ask us for your complimentary beach parking pass) to nearby Harvey’s Beach; this small beach is said to be one of the best in Connecticut. Our Adventure guide (find it on our website) makes it easy to plan it all. At a glance, see what is happening in each month of 2024. For dining, our “Let’s Eat!” guide (also found on our website) is all you need. Of course, breakfast is on us. Your breakfast voucher (one per day of your visit) is good at nearby Mirsina’s.