21c Museum Hotel St Louis
- Pet friendly
- Swimming pool
- Free Wifi
- Bathtub
- Air conditioning
- 24-hour front desk
- Key card access
- Daily housekeeping
- Non-smoking rooms
- Safe
About this property
Comfortable Accommodations: Rooms feature air-conditioning, private bathrooms, and modern amenities such as free WiFi, streaming services, and work desks. Additional comforts include bathrobes, hairdryers, and free toiletries. Wellness and Leisure: Guests can enjoy spa facilities, a wellness center, indoor swimming pool, and fitness room. The hotel offers yoga and fitness classes, a steam room, and a hot tub for relaxation. Dining Experience: The modern restaurant serves Spanish cuisine for dinner, complemented by a bar. American breakfast is available each morning. Outdoor seating areas provide additional dining options. Prime Location: Located in Saint Louis city center, the hotel is 13 mi from St. Louis Lambert International Airport. Nearby attractions include Old Courthouse and Laclede's Landing, each 1.2 mi away.
Couples in particular like the location – they rated it 8.7 for a two-person trip.
Distance in property description is calculated using © OpenStreetMap
Most popular amenities
- Indoor swimming pool
- Free Wifi
- Non-smoking rooms
- Spa
- Fitness center
- Restaurant
- Room service
- Facilities for disabled guests
- Bar

Guest reviews
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Guests who stayed here loved
- Yurina
United States
“Location, facilities (spa and pool), modern design, dog friendly, spacious room(luxury queen)” - Justin
United States
“The staff seemed really nice. The room was comfortable, and the beds felt amazing.” - Aaron
United States
“The entire property along with the staff were phenomenal!” - Amanda
United States
“Check in/out was easy and everyone we encountered was very friendly. Valet employees were super helpful. Hotel was very clean” - Vidoq
United States
“Nice and cozy hotel with lots of art inside. Good amenities, really nice cafe (for breakfast) and lounge bar (for a dinner or drink). Valet parking is another +, they completely changed the approach and now valet parking is not in front of the...” - Peterson
United States
“There was knowledgeable staff. It was a place where if you didn't want to take a car you could walk downtown.” - Chalonda
United States
“Beautiful, clean and comfy. We will definitely stay again when we visit so we can have more time in the hotel. -Loved the 2 workout areas, very clean and well-maintained fitness areas. -Me and my family loved the hot tub & pool. -Enjoyed the...” - Patrick
United States
“We turned our visit into a staycation and it was amazing not having to leave the premises since there was a pool, restaurant, art museum, all in one spot.” - Khadija
United States
“The museum and art around the hotel really made our stay! My son is a budding artist and was truly inspired after we left. The staff took good care of us! The room was spacious… the rooms are perfectly insulated and provide a quiet night’s rest. I...” - Russ
United States
“Room wasn't ready upon arrival (understandable since we booked same day) so they comped us a $70 ticket for the bar. We had a lovely dinner on the house! Also, this was the most pet friendly facility I've ever stayed at. I've got nothing but good...”
Hotel area info
Restaurants
- Idol Wolf
- CuisineSpanish
- Open forDinner
- AmbienceModern
House rules
Child policies
Children of all ages are welcome.
Children 18 and above will be charged as adults at this property.
To see correct prices and occupancy info, add the number and ages of children in your group to your search.
Crib and extra bed policies
Cribs and extra beds aren't available at this property.



The fine print
Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply.