Hotels in Santo Spirito, Florence
Enter your dates and choose from 515 hotels and other places to stay
Featured Hotels in Santo Spirito
Filter by:
Star Rating
Review score
Palazzo Martellini Residenza d'epoca
Palazzo Martellini Residenza d'epoca features accommodations in the center of Florence, a 3-minute walk from Pitti Palace and 600 yards from Strozzi Palace.

Palazzo Ridolfi - Residenza d'Epoca
Located in Florence and with Pitti Palace reachable within a 3-minute walk, Palazzo Ridolfi - Residenza d'Epoca has express check-in and check-out, allergy-free rooms, a shared lounge, free WiFi...

SPIRIT OF FLORENCE Boutique Rooms
SPIRIT OF FLORENCE Boutique Rooms features free Wifi and rooms with air conditioning in Florence.

Althea Rooms
Located on the less touristy side of the Arno River, a 3-minute walk from Piazza di Santo Spirito, Althea Rooms offers free WiFi, and the owners will amaze you with their excellent customer service...

LOFT IN FLORENCE
LOFT IN FLORENCE in Florence offers accommodations with free Wifi, a 5-minute walk from Strozzi Palace, half a mile from Santa Maria Novella, and a 15-minute walk from Palazzo Vecchio.

Geppi's Apartments
Geppi's Apartments features rooms with free Wifi in the center of Florence. There's a private entrance at the apartment for the convenience of those who stay.

Piazza Pitti Palace - Residenza d'Epoca
Set in a historic building and featuring free WiFi throughout, Piazza Pitti Palace offers accommodations in Florence, 328 feet from Pitti Palace.

BSJ15-Borgo San Jacopo Room
In the heart of Florence, BSJ15-Borgo San Jacopo Room offers rooms with free Wifi.

San Pier Novello in Oltrarno
Offering air-conditioned rooms in the Santo Spirito district of Florence, San Pier Novello in Oltrarno is a 12-minute walk from Strozzi Palace.

Toscanelli Residenza d'Epoca
Right in the heart of Florence, Toscanelli Residenza d'Epoca features rooms with free Wifi. There's a private entrance at the guest house for the convenience of those who stay.

Most booked hotels in Santo Spirito in the past month
Popular with guests booking hotels in Florence
Scored out of 10, guest rating 8.5Very Good - What previous guests thought, 1,531 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 8.6Excellent - What previous guests thought, 1,939 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.4Wonderful - What previous guests thought, 1,212 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 8.8Excellent - What previous guests thought, 801 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 8.2Very Good - What previous guests thought, 788 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.2Wonderful - What previous guests thought, 388 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.3Wonderful - What previous guests thought, 882 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.2Wonderful - What previous guests thought, 328 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.2Wonderful - What previous guests thought, 439 reviewsPopular with guests booking hotels in Florence
Scored out of 10, guest rating 9.4Wonderful - What previous guests thought, 211 reviews
The best hotels with breakfast in Santo Spirito
Palazzo Ridolfi - Residenza d'Epoca
Hotel in Santo Spirito, FlorenceBreakfast optionsScored out of 10, guest rating 9.4Wonderful - What previous guests thought, 1,212 reviewsLocated in Florence and with Pitti Palace reachable within a 3-minute walk, Palazzo Ridolfi - Residenza d'Epoca has express check-in and check-out, allergy-free rooms, a shared lounge, free WiFi...
- Scored out of 10, guest rating 9.4Wonderful - What previous guests thought, 211 reviews
In a prime location in the center of Florence, Palazzo Bianca Cappello Residenza d'Epoca is within a 3-minute walk of Pitti Palace and 700 yards of Strozzi Palace.
Hotel Palazzo Guadagni
Hotel in Santo Spirito, FlorenceBreakfast optionsScored out of 10, guest rating 9.2Wonderful - What previous guests thought, 388 reviewsPalazzo Guadagni Hotel is set in a 16th-century building in a quiet square a 5 minute walk from the Ponte Vecchio. It has a roof garden with lovely views.
Palazzo Guicciardini
Hotel in Santo Spirito, FlorenceBreakfast optionsScored out of 10, guest rating 8.8Excellent - What previous guests thought, 801 reviewsDecorated with 16th-century frescoes, Palazzo Guicciardini is located in Florence, a 5-minute walk from Ponte Vecchio. Free Wi-Fi access is available throughout.
Check out other unique places to stay in Santo Spirito
Pet-Friendly Hotels
92 pet-friendly hotels in Santo SpiritoBoutique Hotels
6 boutique hotels in Santo SpiritoGuest Houses
9 guest houses in Santo SpiritoAccessible Hotels
5 accessible hotels in Santo SpiritoB&Bs
14 B&Bs in Santo SpiritoApartments
121 apartments in Santo SpiritoServiced apartments
5 serviced apartments in Santo SpiritoSelf-Catering Accommodations
68 self-catering accommodations in Santo Spirito
Places of interest in and around Santo Spirito
Find hotels near attractions, museums, and other landmarks
Pitti Palace, Florence
MuseumsVia Maggio, Florence
Popular AreasPorta Romana, Florence, Florence
LandmarksCappella Brancacci, Florence
LandmarksConsulate General of Brazil – Florence, Florence
Institutions
More districts like Santo Spirito
Explore hotel options in other areas of Florence
Florence Historic Center
4236 hotelsSanta Maria Novella
1890 hotelsUffizi
641 hotelsSan Marco - Santissima Annunziata
549 hotelsCampo Di Marte
543 hotelsPalazzo Pitti
511 hotelsSanta Croce
506 hotelsSan Lorenzo
364 hotelsFortezza da Basso
341 hotelsDuomo
295 hotels